广西肿瘤医院近10年胃癌临床流行病学分析

Epidemiological characteristics of the gastric cancer in recent 10 years in Guangxi Cancer Hospital

目的:分析广西肿瘤医院近10年胃癌临床流行病学的特点及变化趋势。方法:选取广西肿瘤医院2002年1月1日至2012年1月1日住院治疗的1424例胃癌患者为研究对象,按时间先后分为前5年组(n=519)和后5年组(n=905)2组,对2组患者的年龄、性别、血型和病理学特征构成情况进行回顾性分析。结果:前5年组患者平均年龄54.47±13.45岁,男女比例2.09∶1;后5年组患者平均年龄54.06±13.20岁,男女比例2.10∶1。2组患者年龄和性别无明显变化(P>0.05)。胃癌的发病率男女均随年龄的增长而升高,50-60岁为发病高峰年龄段。2组患者的肿瘤发生部位均以胃窦部为主。在所有胃癌患者中,早期胃癌所占比例均明显低于进展期胃癌(P<0.05)。2组血型分布无明显差异,后5年组低-未分化型胃癌患者比例较前5年组降低。结论:广西壮族自治区胃癌发病年龄有后移趋势,早期胃癌患者比例低,血型可能与肿瘤的生物学行为相关。

Objective：To explore the clinical epidemiologic characteristics and tendency of the gastric cancer in recent ten years in Guangxi Tumor Hospital. Methods：All 1424 patients suffering from gastric cancer in our depart- ment from January 2002 to January 2012 were admitted and divided into two groups：previous 5 years group （n = 519 ） and post 5 years group （ n = 905 ）. Results ： Previous and post 5 years, the two groups of patients with an average age respectively were （54.47± 13.45） and（54.06± 13.20） years. The male to female ratio respectively （2.09：1 ）, （2. 10：1 ）. There was no significant differences of age and gender between two groups （ P 〉 0.05 ）. Both in men and women the inei - dence of gastric cancer gradually increased with age,50 to 60 years old was the peak. The tumor oc- curs mainly in the gastric antrum in two groups. In all patients with gastric cancer, the proportion of early gastric canc- er were significantly lower than advanced gastric cancer（P 〈 0.05）. The distribution of~ blood type was no significant difference between the two groups. The proportion of patients with poorly differentiated gastric cancer in the post 5 years was lower than previous 5 years. Conclusion：The age of onset of gastric cancer have a backward tendency in Guangxi Zhnang Autonomous Region. The proportion of patients with early gastric cancer is low and blood type may be associated with the biological behavior of the tumor.