乌司他丁在急性心肌梗死行PCI治疗患者中的应用

Application of Ulinastatin to AMI patients undergoing PCI therapy

目的:探讨乌司他丁在急性心肌梗死行急诊冠状动脉介入(PCI)治疗患者中的应用方法及临床效果。方法:将100例急性心肌梗死患者随机分为观察组与对照组各50例,对照组给予常规治疗,观察组在此基础上加用乌司他丁治疗,比较两组临床疗效。结果:观察组患者心律失常率明显低于对照组(P<0.01)。结论:乌司他丁能明显降低急性心肌梗死行PCI治疗患者恶性心律失常及住院期间心脏事件发生率,提高其近期生存率。

Objective ： To explore the application method and clinical effect of Ulinastatin in the treatment of patients with acute myocar- dial infarction （ AMI ） by primary percutaneous coronary intervention （PCI ） therapy. Methods ：100 patients with AMI were randomly divided into the observation group and the control group（ 50 cases in each group）. The conventional treatment was given to the patients in the con- trol group;Ulinastatin was used in the observation group based on the conventional treatment. The clinical efficacy was compared between the two groups. Results ：The incidence of arrhythmia was significantly lower in the observation group than the control group（ P 〈 0.01 ）. Conclusion ： Ulinastatin can obviously reduce the incidence of malignant arrhythmia and cardiac events during hospitalization in the patients with AMI treated by PCI therapy and the short -term survival rate will be increased.