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腺病毒载体的研究进展 被引量：4

Advances in studies on adenovirus vector
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摘要 腺病毒(adenovirus,Ad)作为基因表达载体的研制起始于20世纪60年代初,当时病毒学家观察到腺病毒基因组可与猴类病毒40(SV40)基因组杂交,说明腺病毒基因组可承载异源性基因.此后腺病毒逐步发展成一种重要的载体系统,并成功地用于基因治疗的体内外实验和临床试验.目前运用最广的腺病毒载体(adenovirus vector,Adv)是血清5型腺病毒.
作者 施明 王福生 高兰兴
机构地区 中国人民解放军传染病研究所生物工程室 中国人民解放军军事医学科学院卫生学环境医学研究所
出处 《世界华人消化杂志》 CAS 2000年第11期1282-1286,共5页 World Chinese Journal of Digestology
关键词 腺病毒 载体 基因表达 血清诊断 疫苗 基因疗法 Subject headings adenovirus vector gene expression SV40 virus serodiagnosis vaccines gene therapy
分类号 R346 [医药卫生—基础医学]
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参考文献99

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二级参考文献11

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世界华人消化杂志
2000年 第11期

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