320排CT灌注成像在肝癌诊断中的临床应用

The clinical application of 320 rows CT perfusion imaging in liver cancer diagnosis

目的探讨320排CT灌注成像(CTPI)在原发性肝癌(PLC)的血流灌注特点及其诊断价值。方法对103例PLC于介入治疗前行320排CT全肝灌注扫描,获得灌注彩图及其参数,并与正常肝组织比较,评价PLC的CT灌注特点。结果 103例PLC在肝动脉灌流量(HAP)彩图上较周围正常肝组织呈明显高灌注,其中34例呈均匀高灌注,69例呈不均匀高灌注;PLC在门静脉灌流量(PVP)彩图上较正常肝组织呈明显低灌注;肿瘤组织的BF、BV、PS、HAP、HPI参数值均高于肝组织(P<0.05),而MTT、PVP低于肝组织(P<0.05)。结论 320排CTPI能直观、定量地全面反映PLC的血流灌注特点,有助于介入治疗前对PLC作出快速而准确的诊断与评价。

Objective To explore the blood perfusion and its diagnosis value of 320 rows CT perfusion imaging in primary liv- er cancer. Methods To conduct 320 rows whole liver perfusion scan to PLC sufferers before interventional therapy, to acquire their perfusion color drawings and parameters, and then compared to normal liver tissue to evaluate PLC ~s perfusion features. Results For those 103 sufferers, their PLC in HAP color drawing show obviously high perfusion than normal liver tissue. Among them,34 show even- ly high perfusion but 69 show unevenly high perfusion. Their PLC in PVP color drawing shows obviously low perfusion. BF, BV, PS, HAP and HPI parameters of tumor tissue are high than liver tissue （ P 〈 0.05 ） , but MTT and PVP are low than liver tissue （ P 〈 0.05 ）. Con- clusion Whole liver four dimensions perfusion analysis on 320 rows CIPI can fully reflect PLCg blood perfusion features directly and measurably. It can make a quick and correct diagnosis and evaluation on PLC before interventional therapy.