年龄相关性白内障危险因素探讨

Control study on risk factors of age-related cataract

目的探讨可能引起年龄相关性白内障的危险因素，为制定年龄相关性白内障的预防措施提供依据。方法采用1：1病例对照研究方法，对南通市63对年龄相关性白内障及对照进行多变量测量。统计分析采用条件logis—tic回归进行单因素和逐步回归分析。结果单因素分析结果显示吸烟、胆固醇、紫外线、类固醇等药可能是白内障发病的危险因素。饮酒可能是保护因子。在条件logistic逐步回归分析中，眼部其他疾病、胆固醇、白内障家族史、糖尿病家族史、日光下作业最终进入方程。结论年龄相关性白内障的发病与多种因素有关。南通市白内障发病的危险因素基本具有其他地区人群共同的特点。

Objective This study armed at exploring the risk factors for age-related cataract. Methods A 1 ： 1 matched case-control study with 63 pairs on risk factors of cataract was carried out in Nautong. The available data were analyzed by univa- riate and stepwise logistic regression model. Results Single factor analysis showed that smoking, cholesterol, uhraviolet ray, and some other medicine such as steroid may be risk factors. Drinking may be protective factor. Furthermore results of logistic stepwise regression analysis confirm this. Conclusion Age-related cataract is related to many factors. The risk factors of cata- ract in Nantong is more or less the same as other regions.