旋转床模拟推拉动作的心血管效应

Cardiovascular responses to rotation table simulated push-pull maneuver

目的 使用旋转床模拟推拉动作 ,观察推拉动作时人体的生理反应 ,探讨推拉效应的发生机理。 方法 11名受试者在旋转床上经受“直立位 ( +1GZ)→倒立位 ( - 1GZ)→直立位 ( +1GZ)”的模拟推拉动作 ,测定心率 ( HR)、血压 ( BP)、基础阻抗 ( Z0 )、每搏心输出量 ( SV)及总外周阻力( TPR)等生理指标。 结果 在倒立位时 HR、平均动脉压 ( MAP)、舒张压 ( DBP)、Z0 及 TPR较对照降低均有显著性意义 [HR分别为 ( 6 0 .8± 7.9)次 / min与 ( 87.8± 7.4)次 / min,P<0 .0 1;MAP分别为( 83.8± 8.2 ) m m Hg与 ( 91.8± 15 .0 ) mm Hg,P<0 .0 5 ;DBP分别为 ( 6 7.3± 8.3) mm Hg与 ( 77.0±15 .6 ) m m Hg,P<0 .0 5 ;Z0 分别为 ( 2 7.0± 2 .8) Ω 与 ( 2 9.1± 3.3) Ω,P<0 .0 1;TPR分别为 ( 73.15±12 .12 ) k Pa· s· L- 1 与 ( 113.3± 36 .4) k Pa· s· L- 1 ,P<0 .0 1],SV升高有显著性意义 [分别为 ( 15 5 .0± 2 6 .1) m l与 ( 78.7± 19.5 ) ml,P<0 .0 1],SBP有降低趋势 ,但未达显著水平。在再次直立位时 ,HR、MAP、DBP、Z0 及 TPR较对照降低均有显著性意义 [HR分别为 ( 81.9± 8.9)次 / min与 ( 87.8± 7.4)次 / m in,P<0 .0 5 ;MAP分别为 ( 88.1± 13.6 ) mm Hg与 ( 91.8± 15 .0 ) m m Hg。

Objective To observe the physiological responses to pushpull maneuver, and explore the mechanism of pushpull effect. Methods Eleven healthy male volunteers served as subjects. A self developed rotation table was used to simulate the pushpull maneuver by keeping subjects in head up erect position (+1 G Z) for 1 min (as control), then in head down erect position (-1 G Z) for 10 s and again in head up erect position (+1 G Z) for 1 min. Heart rate (HR), blood pressure (BP), basic impedance (Z 0), stroke volume (SV), total peripheral resistance (TPR) of the subjects were monitored during the experiment. Results As compared with control, HR, BP, Z 0, and TPR during -G Z were significantly lowered (P<0.01, P<0.05), while SV was increased significantly (P<0.01). During subsequent +1 G Z, HR, BP, Z 0, and TPR were partly restored, but still significantly lower than those of control (P<0.05, P<0.01). Conclusion It is suggested that the incomplete recovery of HR, TPR, and BP following -G Z may be one of the mechanisms of the pushpull effect.