期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

亚低温治疗对缺氧缺血性脑病新生儿生理学指标和药物代谢的影响 被引量：4

原文传递
导出
摘要 维持恒定的体温对于机体正常生理功能的发挥有决定性作用,体温异常变化（高温或低温）都会对机体造成不利影响.新生儿尤其是早产儿对温度变化最敏感,低体温或寒冷损伤十分常见.亚低温治疗可改善胎龄＞35周的急性围产期窒息缺氧导致的中至重度缺氧缺血性脑病（hypoxic-ischemicencephalopathy,HIE）患儿的远期（直到学龄前期）预后和无病生存率,一系列的随机对照试验已经报道并证实了该观点,且已成为目前发达国家HIE患儿唯一有效的标准治疗措施.
作者 张沂洁 王来栓
机构地区 复旦大学附属儿科医院新生儿科
出处 《中华围产医学杂志》 CAS 北大核心 2013年第12期725-730,共6页 Chinese Journal of Perinatal Medicine
关键词 重度缺氧缺血性脑病 亚低温治疗 新生儿 生理学指标 药物代谢 围产期窒息缺氧 HIE患儿 正常生理功能
分类号 R722.1 [医药卫生—儿科] R454.5 [医药卫生—治疗学]
  • 相关文献

参考文献45

  • 1王来栓,程国强,周文浩,孙金峤,曹云,邵肖梅.亚低温治疗胎龄大于35周龄新生儿缺氧缺血性脑病效果及安全性的荟萃分析[J].中华医学杂志,2012,92(20):1400-1404. 被引量：36
  • 2Edwards AD,Brocklehurst P,Gunn AJ,et al.Neurological outcomes at 18 months of age after moderate hypothermia for perinatal hypoxic ischaemic encephalopathy:synthesis and meta analysis of trial data.BMJ,2010,340:c363.
  • 3Shankaran S,Pappas A,McDonald SA,et al.Childhood outcomes after hypothermia for neonatal encephalopathy.N Engl J Med,2012,366:2085-2092.
  • 4Guillet R,Edwards AD,Thoresen M,et al.Seven to eight year follow-up of the CoolCap trial of head cooling for neonatal encephalopathy.Pediatr Res,2012,71:205-209.
  • 5PerlmanJM,Wyllie J,Kattwinkel J,et al.Neonatal resuscitation:2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations.Pediatrics,2010,126:e1319-1344.
  • 6American Academy of Pediatrics,American Heart Asciation.Neonatal resuscitation textbook.6th ed.Illinois:American Academy of Pediatrics,2011.
  • 7Rudan I,Chan KY,Zhang JS,et al.Causes of deaths in children younger than 5 years in China in 2008.Lancet,2010,375:1083-1089.
  • 8Keller E,Steiner T,Fandino J,et al.Changes in cerebral blood flow and oxygen metabolism during moderate hypothermia in patients with severe middle cerebral artery infarction.Neurosurg Focus,2000,8:e4.
  • 9Sakoh M,Gjedde A.Neuroprotection in hypothermia linked to redistribution of oxygen in brain.Am J Physiol Heart Circ Physiol,2003,285:H17 25.
  • 10Ancora G,Maranella E,Locatelli C,et al.Changes in cerebral hemodynamics and amplitude integrated EEG in an asphyxiated newborn during and after cool cap treatment.Brain Dev,2009,31:442-444.

二级参考文献17

  • 1Jacobs S, Hunt R, Tamow-Mordi W, et al. Cooling for newborns with hypoxic ischaemic encephalopathy. Cochrane Database Syst Rev, 2007 :CD003311.
  • 2Simbruner G, Mittal RA, Rohlmann F, et al. Systemic hypothermia after neonatal encephalopathy : outcomes of neo. nEURO, network RCT. Pediatrics, 2010,126 : e771-778.
  • 3Zhou WH, Chang GQ, Shao XM, et al. Selective head cooling with mild systemic hypothermia after neonatal hypoxic-ischemic encephalopathy: a multicenter randomized controlled trial in China. J Pediatr, 2010, 157:367-372, e1-3.
  • 4Jacobs SE, Morley C J, Inder TE, et al. Whole-body hypothermia for term and near-term newborns with hypoxic-ischemic encephalopathy: a randomized controlled trial. Arch Pediatr Adolesc Med, 2011, 165:692-700.
  • 5Gluckman PD, Wyatt JS, Azzopardi D, et al. Selective head cooling with mild systemic hypothermia after neonatal encephalopathy : multicentre randomized trial. Lancet, 2005, 365:663-670.
  • 6Azzopardi DV, Strohm B, Edwards AD, et al. Moderate hypothermia to treat perinatal asphyxial encephalopathy. N Engl J Med, 2009, 361:1349-1358.
  • 7Shankaran S, Laptook AR, Ehrenkranz RA, et al. Whole-body hypothermia for neonates with hypoxie-Isehemic encephalopathy. N Engl J Med, 2005, 353 : 1574-1584.
  • 8Robertson N J, Nakakeeto M, Hagmann C, et al. Therapeutic hypothermia for birth asphyxia in low-resource settings: a pilot randomized controlled trial. Lancet, 2008, 372:801-803.
  • 9Eicher DJ, Wagner CL, Katikaneni LP, et al. Moderate hypothermia in neonatal encephalopathy: efficacy outcomes. Pediatr Neurol, 2005, 32:11-17.
  • 10Mietzsch U, Parikh NA, Williams AL, et al. Effects of hypoxieischemic encephalopathy and whole-body hypothermia on neonatal auditory function: a pilot study. Am J Perinatol, 2008, 25: 435-441.

共引文献35

同被引文献38

引证文献4

二级引证文献37

中华围产医学杂志
2013年 第12期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部