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关节软骨低氧诱导因子-2α及其相关因子的调控

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摘要 近年来研究发现了HIF-2α在关节软骨细胞代谢的重要作用,其中HIF-2α在(Osteoarthritis,OA)中发挥了核心角色,以HIF-2α为中心维持软骨稳态、血管化、促基质分解、合成相关调控通路分子是研究的相关目标。如未来更多的研究证实其关键作用,将从HIF-2α因子来作为新的靶点药物来治疗骨关节疾病也许是一种新途径。
作者 杨智为 王蕊 汪宗保 陆晴友 徐亚林 陈朝晖
机构地区 安徽中医药大学针灸骨伤临床学院 中山大学附属第一医院骨科 同济大学附属东方医院急诊创伤外科
出处 《中国社区医师（医学专业）》 2013年第20期3-4,共2页
基金 中国博士后科学基金项目(2011M501355)
关键词 关节软骨 低氧诱导因子-2α 相关因子
分类号 R370.2 [医药卫生—病原生物学]
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参考文献11

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二级参考文献12

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共引文献4

中国社区医师（医学专业）
2013年 第20期

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