2型糖尿病患者静滴糖皮质激素时血糖控制的临床观察

Clinical observation of blood glucose control in patients with type 2 diabetes during the intravenous drip of glucocorticoid

目的观察2型糖尿病患者静滴糖皮质激素期间血糖的变化情况。方法 2型糖尿病患者(合并需要使用糖皮质激素的其他疾病)43例,随机分成观察组22例与对照组21例,观察组在静滴糖皮质激素液体中加入胰岛素控制血糖波动;对照组静滴糖皮质激素液体时不加入胰岛素,根据血糖波动情况追加使用胰岛素。观察两组治疗后血糖波动情况及胰岛素用量。结果观察组血糖升高幅度较对照组显著下降,血糖波动低于对照组(P<0.01);观察组胰岛素用量增加幅度减小,胰岛素增加用量少于对照组(P<0.05)。结论选用胰岛素作为基础降糖治疗,按比例在静脉使用糖皮质激素液体组加入胰岛素,可有效防止血糖过高波动,减小胰岛素用量增加幅度。

Objective To observe the change of blood glucose in patients with type 2 diabetes during the intravenous drip of glucocorticoid. Methods 43 patients with type 2 diabetes combined with other diseases which were needed to use glucocorticoid were randomly divided into 22 patients of the observation group and 21 patients of the control group. The patients in the observation group were added insulin in the intravenous glucocorticoid liquid to control the blood glucose fluctuations, and the patients in the control group were not added insulin in the intravenous glucocorticoid liquid, while used insulin according to the blood glucose fluctuations. The blood glucose fluctuations and insulin dosage of the two groups were observed after the treatment. Results Compared with the control group, the blood glucose rise of the observation group decreased significantly, and the blood glucose fluctuations of the observation group was lower than that of the control group （P 〈 0.01）; The insulin dosage rise of the observation group decreased, and the insulin dosage of the observation group was less than that of the control group（P 〈 0.05）. Conclusion Choosing insulin as a basic oral glucose-owering treatment, adding insulin according to the proportion in the intravenous glucocorticoid liquid, which can effectively prevent the hyperglycemia fluctuation, and reduce the insulin dosage rise.