计算机建模在眼科研究中的应用

The Application of Computer Modeling in Ophthalmologic Investigation

人眼的调节机制、眼内压力分布、房水流动情况、眼内温度场分布等特性很难直接测量。建模仿真在眼科学研究中扮演着越来越重要的作用。本文介绍了眼科学研究中主要的计算机建模方法:几何形态建模、物理建模和数学建模。按由整体到局部、从前到后、由外到内的顺序分析了建模仿真在角膜、房水、晶状体、玻璃体、视乳头、巩膜等眼部组织解剖及生理研究中的应用现状。讨论了建模仿真应用到眼科学研究中所存在的问题,指出了未来的发展趋势。

It is very difficult to measure the human eye properties directly, such as the accommodation mechanism, intraocular pressure distribution, the dynamics of aqueous humor flow and the bio-heat transfer in human eyes. Mod eling and simulation may, therefore, play an increasingly important role in the ophthalmologic investigation. The major computer modeling methods, including geometric modeling, physical modeling and mathematical modeling, are introduced in this paper. Modeling and simulation anatomy properties and physiological properties of eye tissues, such as the cornea, aqueous humor and crystalline lens, vitreous, optic nerve head, sciera, are analyzed in the order from global to local, from front to back, from outside to inside. Finally, the problems of computer modeling in oph- thalmologic investigation are discussed, and the development trends of the future are pointed out.