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肾间质纤维化诊断与评估方法的研究进展 被引量:4

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摘要 肾间质纤维化几乎是所有慢性肾脏疾病发展的最终结果,与慢性肾衰竭进展密切相关,是导致终末期肾衰竭的主要病因。肾间质纤维化常伴有肾小管萎缩、间质炎性细胞浸润、成纤维细胞聚积以及间质基质沉积等特征性病理改变。主要发生机制包括.间质成纤维细胞增殖、活化;肾小管上皮细胞转分化为肌成纤维细胞;
作者 何辉 赵明
出处 《中华肾脏病杂志》 CAS CSCD 北大核心 2013年第11期862-865,共4页 Chinese Journal of Nephrology
基金 国家自然科学基金(81170696)
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参考文献30

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二级参考文献14

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