精液与妊娠

Semen and Pregnancy

自首例试管婴儿诞生以来,辅助生殖技术不断取得进步,显微操作技术的应用以及序贯培养基的使用使成功率得到了提高,而与自然妊娠相比,精液的存在与否是其不同之处。精液在形成受精卵、为精子供能方面的作用外是否还有更重要的作用,一直为广大生殖医学学者所研究。本文就精液与妊娠、精液与母体免疫、精液与孕体共同抗原、精液引起的反应等方面进行综述。

From the birthday of the first baby of in vitro fertilization-embryo transfer （IVF-ET）, assisted reproductive technology （ART） continues to make progress. The success rate was improved by the application of micromanipulation technique and sequential medium, but when compared with the normal pregnancy, the existence of semen or not is the difference between them. Pregnancy cannot occur in absence of sperm. Seminal plasma promotes sperm survival, transport. Is there any potential function between semen and female tissues？ This question gained many experts＇ attention. This article review the relationship of semen and pregnancy, semen and maternal immune, antigens shared by semen and conceptus, reproductive related cytokines in semen.