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MALDI-TOF MS直接鉴定原始尿液中的病原菌 被引量:13

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摘要 尿路感染是临床最常见的感染性疾病之一,也是医院获得性感染的主要病因[1].目前国内外诊断尿路感染的“金标准”仍是清洁中段尿培养[2],而此种方法常常需要2~5d才能得出细菌鉴定及药敏结果,不能及时为临床诊断治疗提供病原学依据.基质辅助激光解析电离飞行时间质谱(matrix-assisted laser desorption/ionization time of flight mass spectrometry,MALDI-TOF MS)是近些年来发展起来的一种新型软电离有机质谱,可以根据细菌的组分获得其肽质量指纹谱检测并鉴定细菌,其方便、快速、准确的优点对微生物的鉴定具有重要意义[3-5].
出处 《中华检验医学杂志》 CAS CSCD 北大核心 2013年第11期1042-1044,共3页 Chinese Journal of Laboratory Medicine
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参考文献14

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二级参考文献76

共引文献146

同被引文献149

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