波西普韦合成路线图解
Graphical Synthetic Routes of Boceprevir
摘要
波西普韦（boceprevir，1），化学名为（1R，2S,5S）-N-（4-氨基-1-环丁基-3，4-二氧代丁烷-2-基）-3-[（2S）-2-（叔丁基氨基甲酰氨基）-3，3-二甲基丁酰基]-6，6-二甲基-3-氮杂双环[3．1．0]己烷-2-甲酰胺，是美国Merck公司研发的一种口服有效的丙型肝炎病毒（HCV）NS3／4A蛋白酶抑制剂，2011年4月美国FDA批准上市，商品名Victrelis，临床用于治疗基因I型慢性丙型肝炎（chronic hepatitis C，CHC）。
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2013年第12期1311-1313,共3页
Chinese Journal of Pharmaceuticals
基金
山东省自然科学基金(ZR2009CM016)
参考文献13
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