内蒙古绒山羊Homeoboxc9基因在皮肤毛囊中的表达

Expressed on Hair Follicle of Hoxc9 Gene in Inner Mongolian Cashmere Goat

试验通过原位杂交检测Homeoboxc9(Hoxc9)基因在皮肤毛囊中的表达情况,结果显示Hoxc9在胚胎期75d的上皮细胞中表达,伴随着毛囊的生长发育,Hoxc9基因分别在初级毛囊的毛母质、毛乳头、内根鞘、外根鞘和毛干几个部位表达;在次级毛囊的内根鞘和绒干表达。在这个过程中毛囊角质化细胞大量增殖,表明在毛囊发育中Hoxc9基因对于角质化细胞的增殖可能起一定作用。

The expression of Hoxc9 gene during hair follicle development through in situ hybridization. The results showed that mRNA of Hoxc9 gene began to express firstly in epithelial cell in 75 d. With development of hair follicle, it expressed in hair matrix, dermal papilla, inner root sheath, outer root sheath and hair shaft. Meanwhile, lots of keratinocytes proliferated during this process. This results indicated that Hoxc9 gene might play a role for proliferation of keratinocyte.