乳腺叶状肿瘤30例临床与病理分析

目的分析乳腺叶状肿瘤的病理特征、鉴别诊断及治疗方法等。方法对于30例乳腺叶状肿瘤的相关临床病理资料作回顾性分析。结果30例患者乳腺叶状肿瘤最大的为6.8 cm×8.3 cm×12.4 cm,最小的为1.1 cm×1.5 cm×2.2 cm。本组病例中,属于良性的有23例,交界性的有3例,恶性的4例。免疫组织化学示间质细胞Vim都呈阳性,CD 34阳性3例,CD 117阳性4例,SMA阳性5例,S 100阳性4例,p 53阳性4例,CD 99阳性8例,Ki 67阳性6例。结论乳腺叶状肿瘤有着独特的组织细胞学特征及生物学行为,掌握这些规律,有助于诊断此病,尽量避免误诊误治,降低复发率。

Objective To investigate the pathological features,diagnosis,differential diagnosis of phyllodes tumor and the relationship between treatment and prognosis.Methods The clinical data of 30 cases of breast phyllodes tumors confirmed by pathology were retrospectively reviewed with clinical and pathologic analysis.Results 30 patients with breast t3hyllodes tumor maximum is 6.8 cm× 8.3 cm ×12.4 crn, minimum is 1.1 cm×1.5 cm× 2.2cm.In this group of cases, 23 cases are benign, 3 cases of borderline, 4 malignant.Immunohistochemistry showed interstitial cells of Vimpositive, CD 34 positive 3 cases, CD 117 positive 4 cases,SMA positive 5 cases, S 100 positive 4 cases, p 53 positive 4 cases, CD 99 positive 8 cases, Ki 67 was positive in 6 cases.Conclusion Breast phyllodes tumor with histopathological features and biological behavior,of unique. Master these rules, is helpful to the diagnosis of the disease,and avoid misdiagnosis and mistreatment, reduce the recurrence rate.