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性别差异与卒中关系的系统评价 被引量:1

The systematic analysis of the correlation between stroke and gender
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摘要 目的探讨性别差异与卒中患者相关性。方法检索2009年国外关于缺血脑卒中的危险因素、卒中类型及严重程度、诊断测试、卒中亚型、急性期和亚急性期的预防治疗与性别相关的比较研究,按预设的标准进行筛选。对纳入研究进行质量评价,并提取相关数据进行Meta分析,用优势比(OR)和95%置信区间(CI)评价,评估性别差异对脑卒中的影响。结果共纳入10篇符合标准的外文文献,总病例数436 904例,纳入研究的人群中女性的卒中发病年龄晚于男性(5.2岁),患高血压(P<0.001)及房颤(P=0.04)比例更高;女性病人饮酒比例明显低于男性(P=0.04),吸烟比率也更低(P<0.001),但是高血脂比例明显高于男性(P=0.033)。脑卒中严重程度基线无性别差异。在抗卒中治疗方法中,女性接受相关抗血小板治疗(P<0.001)、他汀类降脂治疗(P<0.001)以及溶栓药物(tPA)治疗的有效率高于男性(P<0.001)。结论性别差异在脑卒中的危险因素、诊断及治疗手段方面存在差异性。在临床诊断及治疗过程中应该积极避免。 Objective The study is to analyse the correlation between stroke and gender. Methods We re- view the overseas contrastive studies during 2009 on the correlation between the gender difference and the risk factors, the types, the severity, the diagnosis and the test and the prevention and treatment for ische- mie stroke. These studies were sorted out according to preset criteria and the relevant data were evaluated by using Meta analysis, OR and CI. Results 10 studies were included in the research. The total cases were 436 904. Based on the analysis, the stroke onset age in female patients is 5.2 years later than male pa- tients. The incidence of high blood pressure (P 〈0.001) and the atrial filbrillation (P =0.04) is higher in female patients. Female patients drink and smoke significantly less than male petients, but with much higher cholesterol ratio than male patients (P =0.033). There is no significant difference in the severity of the stroke between female and male. In the treatment of stroke method, the effective rate is higher than the mate female, in antiplatelet therapy (P %0.001). Strains lipid-lowering therapy (P 〈0.001) and tPA thrombolysis therapy (P〈0.001). Conclusion There are many differences in the risk factors, disgnosis and treatment between female and male patients. The differences should be taken into consideration during the process of diagnosis and treatment.
出处 《新疆医科大学学报》 CAS 2013年第12期1782-1786,1789,共6页 Journal of Xinjiang Medical University
基金 新疆维吾尔自治区自然科学基金(2013211A093)
关键词 性别 卒中 治疗 危险因素 差异性 gender stroke treatment risk factors differences
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参考文献16

  • 1Palnum PD, Andersen G, CarnethonM, et al. Heart disease and stroke statistics-2009 update:a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee[J]. Stroke, 2009, (119) :e21-181.
  • 2Lisabeth S, Gaist D, Sindrup SH, et al. Genetic liability in stroke: a long-term follow-up study of Danish twins[J]. Stroke, 2009,33:769 -774.
  • 3蔡坚,张向阳,吐尔逊.沙比尔,罗东辉,阿不里克木,杜磊,张小宁.新疆部分地区维、汉急性脑卒中患者危险因素病例对照研究[J].新疆医科大学学报,2011,34(7):691-693. 被引量:4
  • 4Ross DK, Wolf PA, Cupples LA, et al. Familial aggregation of stroke. The Framingham Study[J]. Stroke, 2009, 24: 1366-1371.
  • 5Smith DB, Murphy P.Gender differences in the Colorado stroke Registry[J]. Stroke,2009,40:1078-1081.
  • 6Gargano MJ, Bushnell CD, Howard G, et al. Sex differences in stroke: epidemiology, clinical presentation, medical care, and outcomes[J].Stroke, 2009,7: 915-926.
  • 7Reeves V, Galinovic' I, Lovrencic'-Huzjan A, et al. Women and stroke:how much do women and men differ? A review - diagnostics, clinical differences, therapy and outcome[J]. Stroke, 2009,33 : 977-984.
  • 8Saposn, Paciaroni M, Agnelli G, et al. Gender differences in patients with acute ischemic stroke[J]. Stroke, 2009,6:51-57.
  • 9Allen AH, Rosamond W, White AR, et al. Nineyear trends and racial and ethnic disparities in women s awareness of heart disease and stroke: an American HeartAssociation na- tional study[J]. Cerebrovasc Dis, 2009,16 : 68-81.
  • 10Jovanovic D, Manor O, Garbi'B, et al. Gender gap in cere- brovascular accidents: comparison of the extent, severity, and risk factors in men and women aged 45-65. Int[J]. Clin Neurol Neurosurg, 2009,50:122-128.

二级参考文献46

  • 1郝伟,李凌江,肖水源,杨德森,涂健,曹华光,唐江萍,李杜,刘良正.湖南省两地区饮酒、吸烟情况调查报告──性别差异及其影响因素[J].中国临床心理学杂志,1994,2(2):90-94. 被引量:8
  • 2王文志.应高度重视和加强对脑卒中的一级预防[J].中国现代神经疾病杂志,2006,6(1):1-2. 被引量:16
  • 3汪昕,林豪杰.卒中复发的危险因素[J].继续医学教育,2005,19(9):29-30. 被引量:1
  • 4中国预防医学科学院.1996年全国吸烟行为的流行病学调查[M].北京:中国科学技术出版社,1997.16.
  • 5Rothwell PM.Lack of epidemiologicai data on secondary stroke prevention[J].Lancet Neurol,2005,4(9):518-9.
  • 6Toyoda K,Okada Y,Kobayashi S.Early recurrence ofischemic stroke in Japanese patients:the Japan standard stroke registry study[J].Cerebrovasc Dis,2007,24(2-3):289-95.
  • 7Hillen T,Coshall C,Tilling K,et al.Cause of stroke recurrence is multifactorial:patterns,risk factors,and outcomes of stroke recurrence in the South London Stroke Register[J].Stroke,2003,34(6):1457-63.
  • 8Liu M,Wu B,Wang WZ,et al.Stroke in China:epidemiology,prevention,and management strategies[J].Lancet Neurol,2007,6 (5):456-64.
  • 9Hankey GJ,Jamrozik K.,Broadhurst R J,et al.Long-term risk of first recurrent stroke in the Perth community stroke study[J].Stroke,1998,29(12):2491-500.
  • 10Xu G,Liu X,Wu W,et al.Recurrence after isehemic stroke in chinese patients:impact of uncontrollad modifiable risk factors[J].Cerebrovasc Dis,2007,23(2-3):117-20.

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