摘要
根据目前的研究,肿瘤的发生与发展是机体与环境内外因素相互作用的结果,而这一过程涉及癌基因及抑癌基因的异常表达。近年来,国内外学者对MLK3的重要作用进行了广泛深入的研究,尤其是在肿瘤方面的研究日益加深。国内外已有文献报道了MLK3与多种肿瘤发生与发展机制的信号传导有关,但具体机制有待进一步研究。本文通过对近年来国内外相关文献进行归纳总结,对MLK3与肿瘤的关系及其研究进展作一综述。
According to the current study, tumor occurrence and development is the result of the interaction inside and outside the body and the environment factors,but the process involved in the abnormal expression of oncogene and tumor suppressor genes.In recent years,scholars at home and abroad to the important role of. MLK3 in-depth research,especially in the tumor research deepens.Articles at home and abroad have reported MLK3 with a wide variety of tumor occurrence and development mechanism of signal transduction related,but the specific mechanism needs further research.This paper paper summarizes related literature at home and abroad in recent years,to MLK3 its relationship with tumor and its research progress were reviewed.
