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MACC1、HGF/c-Met和EMT在促进恶性肿瘤侵袭转移机制中的相关性研究 被引量：2

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摘要 结肠癌转移相关基因1（metastasis-associated in colon cancer-1,MACC1）是一个在多种恶性肿瘤中调控肿瘤生长和转移的重要基因.MACC1通过调控肝细胞生长因子（hepatocyte growth factor,HGF）/间质向上皮转化因子（mesenchymal-epithelial transition factor,c-Met）信号通路诱导上皮向间质转化（epithelial-mesenchymal transition,EMT）,促进肿瘤细胞的迁移、浸润和转移.因此,本文将MACC1、HGF/c-Met和EMT三者结合在一起,探索三者与肿瘤侵袭转移的相关性.
作者 祝倩倩 朱正秋
机构地区 徐州医学院研究生学院 徐州医学院附属医院肿瘤科
出处 《徐州医学院学报》 CAS 2013年第11期792-794,共3页 Acta Academiae Medicinae Xuzhou
关键词 MACC1 HGF c-Met信号通路 EMT 肿瘤浸润 肿瘤转移
分类号 R730.1 [医药卫生—肿瘤]
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徐州医学院学报
2013年 第11期

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