超声引导下小剂量凝血酶注射治疗医源性股动脉假性动脉瘤

Ultrasound-guided injection with a small dose of thrombin in treatment of iatrogenic femoral pseudoaneurysm

目的研究超声引导下凝血酶注射在医源性股动脉假性动脉瘤治疗中的应用价值。方法在彩色超声多普勒引导下,采用21G PTC针经皮穿刺,对2010年5月-2013年4月本院介入超声科的39例医源性股动脉假性动脉瘤患者瘤内注射凝血酶(250 U/ml,总量均≤150 U)。结果 39例均成功行超声引导下凝血酶注射治疗,瘤腔内血流信号均消失,但3例术后瘤颈处可见少许血流信号,术中、术后无并发症发生,术后无复发。结论超声引导下凝血酶注射治疗医源性股动脉假性动脉瘤操作简便、临床疗效可靠、并发症少、复发率低,临床应用价值较高。

Objective To study the application of ultrasound-guided thrombin injection （UGTI） in treatment of iatrogenic femoral pseudoaneurysm （IFPA）. Methods Thirty-nine IFPA patients admitted to our department from May 2010 to April 2013 were included in this study. The patients were injected with 250 U/ml thrombin （the total dose ≤ 150 U） by percutaneous puncture using the 21G PTC needle. Results The UGTI was successful in the 39 patients with no recurrence after operation and no complication during and after operation. The blood flow signals in tumor cavity disappeared except a small number of few blood flow signals in tumor neck in 3 patients after UGTI. Conclusion UGTI is a simple and reliable treatment modality for IFPA with minimal invasiveness and a low complication and recurrence rate, and can thus be widely applied in clinical practice.