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急性冠脉综合征生化标记物研究中的蛋白质组学应用

Application of proteomic techniques in research of acute coronary syndrome biochemical markers
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摘要 急性冠脉综合征(acute coronary syndrome,ACS)病理生理机制的复杂性需要探索更多新的生化标记物为ACS的早期诊断、治疗和预后评估提供有利信息。蛋白质组学技术的发展为多标记物的研究和新标记物的探索提供了便利。利用高通量的蛋白质组学技术研究ACS患者的血液、动脉粥样硬化组织以及心肌组织可以了解动脉粥样硬化的病理生理机制,从而发现ACS新的早期诊断和危险分层生化标记物。本文就蛋白质组学技术在ACS生化标记物中的应用进展进行综述。
作者 董剩勇 曾强
出处 《解放军医学院学报》 CAS 2013年第12期1293-1297,共5页 Academic Journal of Chinese PLA Medical School
基金 国家科技支撑计划项目(2012BAI37B04)~~
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