鼻咽癌患者放射治疗前后记忆的变化

The change of memory before and after radiotherapy for patients with nasopharynegeal carcinoma

目的 研究鼻咽癌病人放射治疗前后记忆力的变化,探讨用记忆商作为放射治疗中早期发现中枢神经系统损害的指标的可能性。方法 对21例首发并且只接受^(60)Co放射治疗的鼻咽癌病人在治疗前后分别进行记忆商测定。结果 21例病人放射治疗后的量表分和记忆商较治疗前有明显下降,记忆测验的各分项量表分除指向记忆在治疗前后无差异外,其余联想学习、图象自由回忆,无意义图形再认和人像特点回忆等四项在治疗后均较治疗前有明显下降。结论 鼻咽癌病人在接受放射治疗后记忆商较放射治疗前有明显下降,记忆商作为鼻咽癌放射治疗中中枢神经系统受损害的一个观察指标是有其可行性的。

Objectives: To investigate the change of memory quotient (MQ) before and after radiotherapy and the probable relationship between MQ and early radiation injury of central nervous system (CNS). Method: Memory test was used to assess the MQ of 21 patients with nasopharyngeal carcinoma before and after the single treatment with 60Co γ-ray. Results: The total scores and the MQ of the 21 patients were lower significantly after radiotherapy than before. The memory test scores of four items, i. e association tests, picture memory, meaningless graph memory and portrait character recall, except directional memory, were lower significantly after radiotherapy than before. Conclusion: It is acceptable to assess the radiation injury of CNS during radiotherapy for patients with nasopharyngeal carcinoma.