171例糖尿病肾病患者危险因素分析

Analysis of the Risk Factors in 171 Patients with Diabetic Nephropathy

目的 :探讨与糖尿病肾病 (DN)发病有关的危险因素。方法 :对 1997～ 1998年间山东沿海地区糖尿病血管并发症调查中的 40 8例 2型糖尿病患者 (其中有 DN者 171例 ,无 DN者 2 37例 )进行分析研究。结果 :DN组年龄、病程、血糖、血压、血脂、纤维蛋白原水平均高于无 DN组 ,视网膜病变发生率及冠心病发生率显著高于无 DN组(P均 <0 .0 0 1)。多元线性回归分析显示病程、纤维蛋白原、甘油三酯、收缩压升高与 DN发病显著正相关。结论 :积极控制血压、血糖、纠正血脂紊乱等是预防和延缓 DN发生和发展的重要措施。

To analyse the diabetic nephropathy(DN) and its related irsk factors from diabetic vascular complication study in Shandong sea board.171 of them were found to have DN and 237 were non DN.The results showed that the older age,duration,glucose,blood pressure level,fibrinogen,triglyceride(TG) and cholesterol of DN group were significantly higher than non DN group.DN group was significantly higher in the ocerrence of diabetic retinopathy,coronary heart disease than that non DN group.Using multiple regression analysis showed that the significant related factors were duration,high fibrinogen,high TG and high systolic presure for DN.The results suggest that close control and correction of these abnormalities were very important to prevent diabetic vascular complications.