椎旁神经阻滞联合医用三氧注射治疗老年患者胸腰背部带状疱疹后遗神经痛的效果

Efficacy of paravertebral block combined with medical ozone injection in the treatment of elderly pa- tients with postherpetic neuralgia

目的评价椎旁神经阻滞联合医用三氧注射治疗老年患者带状疱疹后遗神经痛的效果。方法胸腰背部带状疱疹后遗神经痛患者94例，年龄65～74岁，随机分为A、B两组（n=47），A组采用椎旁神经阻滞治疗，B组给予相同椎旁神经阻滞，同时椎旁注射40％的医用三氧。分别于治疗前（T1）、治疗后24h（T2）、治疗后1个月（T3）时以VAS法进行疼痛评分，于T2、T3时行疗效评定。结果两组患者经过2个疗程治疗后疼痛较治疗前明显好转（P〈0．05），T2、T3时点B组VAS评分均较A组降低（P〈O．05），T2、T3时B组临床治愈率及有效率明显高于A组（P〈0．05），B组羟考酮缓释片使用剂量较A组明显减少（P〈0．05）。结论椎旁阻滞联合医用三氧注射可显著缓解老年患者带状疱疹后遗神经痛，其效果优于单纯椎旁神经阻滞治疗。

Objective To investigate the efficacy of paravertebral block combined with para- vertebral medical ozone injection in elderly patients with postherpetic neuralgia. Methods Ninety- four patients with postherpetic neuralgia, aged 65-74 years, were randomly divided into two groups. The patients in group A received only paravertebral block, and in group B received paraver- tebral block combined with medical ozone injection. Pain level （VAS） was scored before the treat- ment （T1）, at 24 h （T2） and one month （T3） after the treatment respectively （VAS）. Results VAS was significantly lower in group B than that in group A at T2, T3 （P〈0.05）. Compared with group A, oxycodone hydrochloride doses were significantly decreased in group B （P〈0.05）, the clinical cure rate and effective rate were significantly higher in group B at T2, T3 （P〈0.05）. Con- clusion Paravertebral block combined with medical ozone injection can effectively relieve the posther- petic neuralgia in elderly patients.