^(18)F-FDGPET/CT对脑转移瘤所致交叉性小脑神经机能联系不能的研究

^(18)F-FDG PET / CT Evaluation of Crossed Cerebellar Diaschisis in Brain Metastases

【目的】观察大脑转移瘤所致交叉性小脑机能联系不能(CCD)的18F-FDG PET/CT的表现以及探讨丘脑在CCD发生的作用。【方法】回顾性分析218例脑转移瘤患者的18F-FDG PET/CT的表现,根据脑转移灶是否侵犯丘脑分成两组,比较两组患者CCD的发生率;比较不同脑转移瘤数量的患者CCD发生率。【结果】218例脑转移患者中,24例发生CCD,发生率为11.0%。单发脑转移患者47例,CCD发生3例;双发脑转移患者56例,CCD发生5例;多发脑转移患者115例,CCD发生16例,差异不具有统计学意义。其中丘脑受侵患者19例,CCD发生19例;转移瘤未累及丘脑者199例,发生CCD 5例,差异具有统计学意义。【结论】脑转移瘤数量的多少并不能影响CCD的发生;脑转移瘤侵犯丘脑可导致CCD的发生,丘脑可能是CCD发生的关键部位。

[Objective] To observe the value of 18F-FDG PET/CT in detecting crossed cerebellar diaschisis （CCD） in brain metastases and to study the effect of the thalamus in CCD.[Methods] A retrospective analysis of 218 cases of patients with brain metastases of 18F-FDG PET/CT,according to brain metastases whether infringement of the thalamus was divided into two groups.The incidence of CCD from two groups of the patients were compared.[Results] Among 218 patients with brain metastases 24 cases occurred CCD,the rate was 11.0%.Thalamus involvement in 19 patients,all occurred CCD; Thalamus was not invaded in the other 199 patients,only 5 cases of patients with CCD.Two groups of patients with CCD with a statistically significant difference.47 cases of patients with single brain metastasis,3 cases occurred CCD ; 56 cases of patients with double brain metastasis,5 cases occurred CCD.115 cases of patients with multiple brain metastasis,16 cases occurred CCD.The difference was not statistically significant.[Conclusion] Thalamus may be a key component of the CCD occurs.