摘要
目的 探讨“国人缺血性心血管病十年发病危险评估方法”在中年体检者中的应用价值.方法 应用“国人缺血性心血管病十年发病危险评估方法”对1203名35~59岁健康体检者心血管病10年发病的绝对危险和相对危险进行评估和相关分析.结果 (1)中年体检者10年缺血性心血管病发病的绝对危险均值为1.30%±1.80%,其中绝对危险≥5%的45名(3.7%);(2)中年体检者缺血性心血管病相关危险因素(收缩压≥140 mm Hg、舒张压≥90 mm Hg、体质指数≥24 kg/m2、总胆固醇≥5.2 mmol/L、空腹血糖≥7.0 mmol/L、吸烟)的检出率男性高于女性,差异均有统计学意义(x2=26.942,P<0.01;x2=29.250,P< 0.01;x2=233.325,P< 0.01;x2=5.510,P=0.022;x2=5.730,P=0.015;x2=65.009,P<0.01);(3)10年缺血性心血管病发病的绝对危险≥5%的人群各项心血管危险因素的检出率均高于发病绝对危险<5%的人群,差异均有统计学意义(x2=239.62,P<0.01;x2=10.78,P<0.01;x2 =36.40,P<0.01;x2 =35.19,P<0.01;x2 =25.42,P<0.01;x2 =4.98,P=0.034);(4)不同年龄组10年缺血性心血管病发病相对危险在平均水平倍数≤1和>1间、理想水平倍数≤1和>1间比较,差异均有统计学意义(x2 =52.032、160.077,均为P<0.01).结论 “国人缺血性心血管病十年发病危险评估方法”已成为评估我国居民心血管病发病危险的重要工具.10年缺血性心血管病发病的绝对危险在公共卫生领域有重要指导意义,而相对危险对个体的临床综合干预更具指导意义.
Objective To investigate the clinical value of Risk Assessment Tool for Estimating l0-year Risk of Having an ischemic cardiovascular disease (ICVD) in middle-aged volunteers.Methods A total of 1203 healthy volunteers aged from 35 to 59 that satisfied the recruit standards were collected.The absolute and relative 10-year risks of ICVD were estimated and their relationships were analyzed.Results (1) The average of absolute 10-year risks of ICVD in the middle-aged volunteers was 1.30% ± 1.80% and the number of the absolute 10-year risks of ICVD≥5% was 45 (3.7%),respectively.(2) The detection rates of ICVD risk factors of middle-aged males were significantly higher than those of females,which included systolic pressure ≥ 140 mm Hg (x2 =26.942,P 〈 0.01),diastolic pressure ≥ 90 mm Hg (x2 =29.250,P 〈 0.01),body mass index ≥ 24 kg/m2 (x2 =233.325,P 〈 0.01),total cholesterol ≥ 5.2 mmol/L (x2 =5.510,P =0.022),fasting blood glucose ≥7.0 mmol/L (x2 =5.730,P =0.015) and smoking (x2 =65.009,P 〈 0.01).(3) The detection rates of ICVD risk factors in those whose absolute 10-year risks of ICVD higher than 5% were significantly higher than those absolute 10-year risks of ICVD lower than 5% (x2 =239.62,P〈0.01;x2 =10.78,P〈0.01;x2 =36.40,P〈0.01;x2 =35.19,P〈0.01;x2 =25.42,P 〈 0.01 ; x2 =4.98,P =0.034).(4) The relative 10-year risks of ICVD between average level ratio ≤ 1 and 〉 1 in different age groups was significantly different (x2 =52.032,P 〈 0.01),the significant difference also existed between ideal level ratio ≤ 1 and 〉 1 (x2 =160.077,P 〈 0.01).Conclusions The risk assessment tool for estimating l0-year risk of having an ICVD is an important method to assess the risk level of ICVD.The absolute 10-year risk of having an ICVD is meaningful in public health while the relative 10-year risk more useful in clinical treatment for individual.
出处
《中国心血管杂志》
2013年第6期441-444,共4页
Chinese Journal of Cardiovascular Medicine
关键词
心血管疾病
危险性评估
中年人
体检
Cardiovascular diseases
Risk assessment
Middle aged
Examination