前蛋白转化酶枯草溶菌素9及其单克隆抗体调脂研究进展
PCSK9 and monoclonal antibody inhibitors of PCSK9: focus on lipid management
摘要
2003年,法国学者Abifadel等首次报道前蛋白转化酶枯草溶菌素9(proproteinconveasesubtilisin/kexintype9,PCSK9)基因突变引起常染色体显性高胆固醇血症(autosomaldominanthypercholester0Iemia,ADH)。
出处
《中国心血管杂志》
2013年第6期473-476,共4页
Chinese Journal of Cardiovascular Medicine
关键词
前蛋白转化酶枯草溶菌素9
受体
LDL
血脂异常
抗体
单克隆
Proprotein convertase subtilisin/kexin type 9
Receptors, LDL
Dyslipidemias
Antibodies, monoclonal
参考文献27
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