右美托咪定辅助喉罩全麻对老年全髋关节置换术术后躁动的影响

Influence of dexmedtomidine on emergence agitation undergoing total hip replacement surgery

目的观察右美托咪定辅助喉罩全麻对老年全髋关节置换手术术后躁动的影响。方法选择我院2012年1月至2013年3月接受全髋骨关节置换手术患者60例,随机分为观察组和对照组,每组30例。两组均使用喉罩全麻,在手术结束前30 min观察组患者静脉泵入右美托咪定,对照组患者静脉泵入生理盐水,记录两组患者血流动力学指标变化和苏醒期躁动的发生率。结果观察组患者的血压、心率等指标很快恢复到正常水平,而对照组患者恢复较慢,拔管5 min后仍与基准水平存在差距;观察组全麻苏醒期躁动发生率为3.33%,对照组为13.33%,两组比较差异有统计学意义(P<0.05)。结论右美托咪定辅助喉罩全麻用于老年全髋关节置换手术,可以增强血流动力学的稳定性,降低术后躁动发生率。

Objective To investigate the influence of dexmedtomidine on emergence agitation（EA） undergo- ing total hip replacement surgery. Methods 60 patients undergoing total hip replacement surgery in our hospital from January 2012 to March 2013, were randomly divided into observation group and control group at 30 cases in each group. Both groups used the laryngeal mask anesthesia at 30 rain before the end of surgery. Patients in observation group were subjected to intravenous dexmedtomldine, while control group received intravenous normal saline. The he- modynamic indexes and the incidence of emergence agitationin of the two groups were recorded. Results The patients＇ blood pressure, heart rate and other indicators in observation group soon returned to baseline levels, while the control group recovered more slowly, and the indexes above did not return to baseline levels in control group 5 mins later. The rate of EA in observation group was 3.33% , while it was 13.33% in control group,there were significant differences between the two groups （ P 〈 0.05 ）. Conclusion Dexmedetomidine auxiliary laryngeal mask anesthesia in elderly hip replacement surgery can enhance hemodynamic stability, and reduce the rate of postoperative agitation.