得宝松皮损内注射治疗疥疮结节的临床疗效分析

Analysis of clinical efficacy of intralesional injection of diprospan in the treatment of nodular scabies

目的观察皮损内注射得宝松与外用卤米松乳膏治疗疥疮结节的临床疗效。方法将已确诊的60例疥疮结节患者随机分为2组,A组30例(198个结节)应用得宝松皮损内注射治疗,B组30例(186个结节)外用卤米松乳膏治疗,两组患者均观察6周。结果 A组痊愈198个结节(有效率100%),B组痊愈154个结节(有效率86.56%)。A组有效率高于B组,两组比较差异有统计学意义(P<0.01)。结论得宝松与卤米松乳膏相比,具有止痒迅速、结节消退快、复发率低的特点,且无明显不良反应,是治疗疥疮结节更加安全、有效的方法。

Objective To observe the clinical efficacy of intralesional diprospan injecting and topical using of halometasone cream in treating nodular scabies. Methods 60 patients with nodular scabies were randomly divided into two groups. Group A （30 patients, 198 noddies） ： intralesional diprospan injecting. Group B （30 patients, 186 nodules） ： topical using of halometasone cream. The patients of the two goups were treated for 6 weeks. Results The effective rate of group A was higher than that of group B（ 100% vs. 86. 56% ） ,there was statistical difference between the two groups ,P 〈 0. 01. Conclusion Compared with halometasone cream, diprospan has better efficacy in relieving itching quickly, subsiding nodules quickly, lower recurrence rate with no significant adverse effects, and it is more safer, and ef- ficient in treating nodular scabies with diprospan.