摘要
目的调查降糖药在老年糖尿病患者中的使用情况并评价其合理性,为临床合理用药提供指导。方法将2012年5-10月在我院出院的343例糖尿病患者分为老年组(232例)和非老年组(111例),比较降糖药在两组中的具体使用情况。结果老年组药品大类使用频率排序前3位的分别为α-糖苷酶抑制剂、胰岛素及其类似物和双胍类。两组α-糖苷酶抑制剂和双胍类以及阿卡波糖和二甲双胍的使用例数的比较,差异有统计学意义(P<0.01)。结论老年人在具体降糖药品种的选择上有其显著的特征。医师需要重视药品费用和药品选择,给予老年人个体化的用药方案,达到合理用药的目标。
Objective To investigate the use of specific antidiabetic drugs in the elderly diabetic patients and evaluate its rationality to provide reference for clinical rational drugs use. Methods 343 diabetic patients in our hospi- tal from May 2012 to October 2012 were divided into older group ( n = 232 ) and non-elderly group ( n = 111 ). The va- rious drugs used in the two groups was compared. Results In older group ,3 kinds of frequently used categories were ct-glycosidase inhibitors, insulin and its analogs and biguanides. There was significant difference between the two groups in the use of α-glycosidase inhibitors, biguanides, acarbose and metformin ( P 〈 O. O1 ). Conclusion Elderly patients have obvious characteristics on the choice of specific drug. Doctors need to pay more attention to the cost of drug and drug choice in the clinical work, set special administration plan for the elderly patient, and really achieve the goals of ra- tional drugs use.
出处
《实用药物与临床》
CAS
2013年第11期1115-1118,共4页
Practical Pharmacy and Clinical Remedies