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粤语版全科医生认知功能评估量表在广州地区的应用

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摘要 目的 探讨粤语版全科医生认知功能评估量表(GPCOG)在广州地区用于痴呆筛查的信度、效度及应用价值.方法 在广州地区随机选择185例研究对象(痴呆组103例,正常对照组82例),采集人口学资料、病史和辅助检查结果,以美国精神病学会〈精神疾病诊断与统计手册〉修订第4版(DSM-Ⅳ-R)的痴呆诊断标准作为判断标准,使用粤语版GPCOG、简易精神状态检查量表(MMSE)、日常生活能力量表(ADL)等量表进行评估,分析粤语版GPCOG的信度、效度和相关诊断指标.结果 粤语版GPCOG患者部分的内部一致性Cronbach′α系数为0.710,标准化后Cronbach′α系数为0.842,重测信度为0.921.粤语版GPCOG与MMSE评定结果的Pearson相关系数为0.838,与ADL的相关系数为-0.746.粤语版GPCOG筛查痴呆的灵敏度为91.3%、特异度为87.2%,约登指数为0.79,阳性预测值为90.4%,阴性预测值为88.3%,ROC曲线下面积(AUC)为0.896(95%CI:0.816~0.949),标准误为0.031 2.粤语版GPCOG平均耗时为(245±87)s,MMSE平均耗时(465±162)s,两者比较差异有统计学意义(P〈0.01).结论 粤语版GPCOG具有良好的信度、效度和诊断价值,与MMSE比较,操作更简便、省时,适合广州地区的医生给中老年人进行认知功能评估,是一种有效的痴呆筛查工具.
出处 《广东医学》 CAS CSCD 北大核心 2013年第22期3483-3485,共3页 Guangdong Medical Journal
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