2839例术中冰冻切片诊断与术后石蜡切片诊断的对比研究

Comparative study between pathological diagnosis of intraoperative frozen section and postoperative paraffin section of 2839 cases

目的:研究术中冰冻病理诊断的确诊率,分析误诊的原因及减少误诊的方法。方法:回顾性分析2 839例病变的术中冰冻切片与术后制作的常规石蜡切片的诊断结果。结果:与石蜡切片比较,冰冻切片诊断总的确诊率为96.16%,恶性肿瘤的确诊率为94.74%,良性肿瘤的确诊率为96.73%,交界性肿瘤的确诊率为87.76%,误诊率为0.92%。结论:术中冰冻切片病理诊断是术中确定病变性质的有效方法,对术中选择适当的手术方案有重要的影响。

Objective：To study the pathological diagnosis rate of intraoperative frozen section and to analyze the causes of misdiagnosis and to explore methods to reduce misdiagnosis.Methods：Retrospective analysis were applied to the diagnosis of intraoperative frozen section and paraffin section in 2 839 cases of lesions.Results：Compared with paraffin,the total diagnosis rate of frozen section was 96.16% and the diagnosis rate of malignant tumor was 94.74%.The diagnosis rate of benign tumors was 96.73% while the diagnosis rate of borderline tumor was 87.76% with the rate of misdiagnosis being 0.92%.Conclusion：The results suggest that intraoperative frozen section pathological diagnosis is an effective method to determine the nature of the lesions in operation,and has important implications on selecting the appropriate surgical plan.