慢性疼痛并发抑郁症和焦虑症的治疗研究

Therapy Research on Chronic Pain Complicated with Depression and Anxiety

目的:探讨中西医结合治疗慢性疼痛患者并发抑郁、焦虑症的临床疗效。方法:将122例患者按随机数字表法分为治疗组和对照组。治疗组61例依据中医辨证口服中药治疗,对照组61例使用盐酸氟哌噻吨片治疗。于治疗前、治疗8周后,采用疼痛视觉模拟评分(VAS)评定患者的疾病程度,使用17项汉密尔顿抑郁量表(HAMD)和汉密尔顿焦虑量表(HAMA)分别评定患者的抑郁和焦虑状况。结果:治疗前两组患者疼痛程度差异、HAMD和HAMA评分无统计学意义(P>0.05);治疗8周后疼痛程度差异、HAMD和HAMA评分有统计学意义(P<0.05)。结论:慢性疼痛患者并发的抑郁和焦虑症状中医药治疗效果好,不良反应小。

Objective： To study the effect of Chinese and western medicine treatment of chronic pain patients complicated with depression and anxiety. Methods ：122 patients were divided into the treatment group and the control group. The treatment group of 61 cases were given pure Chinese medicine, and the control group of 61 cases were treated with Deanxit. Before and 8 weeks after treatment,visual an- alogue scale （VAS） was used to assess the degree of disease, and the Hamilton depression rating scale （HAMD 17 items） and Hamil- ton anxiety scale （HAMA） were used to assess the patients＇ depression and anxiety respectively. Results ：The pain intensity difference of two groups patients before treatment,Hamilton depression rating scale （HAMD） and Hamilton anxiety scale （HAMA） score had no statistical significance （P 〉 0. 05 ） ;The pain intensity difference of the two groups after treatment of 8 weeks, Hamilton depression rating scale （HAMD） and Hamilton anxiety scale （HAMA） score were statistically significant （ P 〈 0.05 ）. Conclusion ： The effect of chronic pain in hospital patients complicated with depression and anxiety symptoms treated by traditional Chinese medicine is good, and the side effect is small.