长方形无支架心包二尖瓣的生物力学分析

Biomechanical Analysis of Quadrate Stentless Pericardial Mitral Valve

通过建立长方形无支架心包二尖瓣的几何模型,利用有限元方法分析,仿真二尖瓣开启、关闭状态,计算左心室舒张期与等容舒张期的静态应力分布,仿真得到前后瓣叶的形变与体外流体动力学实验中实际形变结果一致;前后瓣叶应力分布比较均匀,最大应力出现在瓣环缝合区与瓣叶基部,与医学临床中二尖瓣易发生撕裂的位置相吻合.此模型及有限元方法分析合理有效,其分析结果可为这种人工二尖瓣的设计与优化提供理论依据.

The stress level of the mitral valve is important for the service life of biological mitral valve,so it has important practical significance to analyse mitral valve＇s stress distribution.We have established the geometric model of the stentless pericardial mitral valve and define the material properties to obtain the finite element model.The finite element algorithm is used to simulate its closure processand to analyze the static stress contours of mitral valve.In our simulation,the deformation of the anterior leaflet and the posterior leaflet remained consistent with the results of vitro fluid dynamics experiment; The stress of leaflets is evenly distributed,the maximum stress occurs at the base of the valve and the suture zone area,which corresponds to with the position that is easy to cleave in medical clinical manifestations.Our model provides theoretical foundation for the design of artificial mitral valve.