布地奈德阶梯雾化辅助治疗小儿急性感染性喉炎疗效观察

Clinical Observation of Budesonide Ladder Atomizing Inhalation on Treatment of Infantile Acute Infectious Laryngitis

目的:观察布地奈德混悬液(普米克令舒)阶梯雾化吸入辅助治疗小儿急性感染性喉炎的疗效。方法:将100例小儿急性感染性喉炎患儿按随机数字表法分为观察组52例和对照组48例,两组均给予相同综合治疗包括对症治疗、抗感染、抗炎等,同时加用布地奈德混悬液,≤1岁每次0.5 mg,>1岁每次1 mg,加生理盐水至3 mL雾化吸入:对照组给予常规雾化治疗,即2次/日;观察组给予阶梯雾化治疗,即0、20、40 min各雾化吸入一次,之后每8 h一次,第2天改为常规雾化。两组患儿均治疗至症状体征完全消失(治愈)后出院,治疗期间对两组进行相同的护理。观察用药后患儿症状体征改善情况,并于治疗24 h后比较两组疗效。结果:总有效率观察组100.0%,对照组95.8%,两组比较差异无统计学意义(P>0.05);平均住院时间观察组3.7 d,对照组5.3 d,两组比较差异有统计学意义(P<0.05)。结论:急性感染性喉炎患儿在对症治疗、抗感染、抗炎等综合治疗同时,加用布地奈德混悬液阶梯雾化辅助治疗并给予正确的护理指导,可缩短住院时间,安全有效。

Objective： To observe the effect and nursing of budesonide ladder atomizing inhalation nebulizer in children with acute infectious laryngitis. Methods： One hundred cases of children with infantile acute infectious laryngitis were divided into an observation group （52 cases ） and a control group （48 cases ） by the stochastic indicator method. The two groups were given comprehensive treatment, such as anti-infection, anti-inflammatory, and budesonide suspension, 0.5 nag each time under one year of age, 1 mg each time above one year of age, with saline to 3 mL for aerosol inhalation . The control group received conventional atomization, twice a day; the observation group was given ladder atomization inhalation at 0 minutes, 20 minutes, 40 minutes, 8 hours, 16 hours and 24 hours; then switched conventional atomization twice a day from the second day. During the treatment, the two groups received the same nursing care. The symptoms and signs in children after medication were observed. The curative effects after 24 hours of treatment were compared. Results： The total dfficience of the observation group is 100%, which was higher than that of the control group （95.8%）, the length hospitalization of the observation group was 3.7 days, which was shorter than that of control group （5.3 days） ; Significant differences were found after the treatment between the two groups in efficacy and length of hospitalization （ P 〈 0. 05 ）.Conclusions： Budesonide ladder atomizing inhalation nebulizer in children with acute infectious laryngitis could shorten the length of hospitalization. It is safe and efficient.