颅面部骨纤维异常增殖症的研究进展

Craniofacial fibrous dysplasia: a systematic review

骨纤维异常增殖症(FD)是一种良性骨内病变,病灶中正常的骨和骨髓被异常增生的纤维组织和随意排列的编织骨所替代。颅面骨是病变最常发生的部位,由于颅面部解剖结构复杂、腔隙孔道多,视病变的部位和程度,临床表现多样,治疗涉及多个临床学科。另外,病变的生长方式无法预测,也增加了治疗的难度。手术有两种截然不同的方式,保守手术修整和根治性切除手术,对手术方式的选择存有一定争议。本文就颅面部FD诊断、治疗方法的选择及新技术应用等方面的进展进行综述。

Fibrous Dysplasia （FD） is a benign lesion in which normal bone and marrow are replaced by fibrous tissue and woven bone. The most common locations are the craniofacial bones, which clinical behavior may vary and treatment need muhidisciplinary. Surgical treatment has two different ways, conservative therapy and radical excision followed by immediate reconstruction. The indications of surgical management in craniofacial fibrous dysplasia are controversial. This Paper presented recent advances in diagnosis, treatment strategies and advanced technology in the management of fibrous dysplasia.