凝血四项指标在围产期孕妇中的检测及其意义

目的:观察凝血四项指标在围产期孕妇中的变化及其临床意义。方法:收集2012年7～12月在江苏泰州市人民医院行产前检查的围产期孕妇100例和健康非孕妇100例,采用sysmex全自动血凝仪对其行凝血功能指标凝血酶原时间(PT)、部分凝血活酶时间(APTT)、凝血酶时间(TT)、纤维蛋白原(FIB)检测,并进行统计分析。分析各组指标之间有无差异性。结果:与对照组相比,围产期孕妇组PT显著降低,两者比较有统计学差异(t=10.806,P<0.001);APTT亦显著低于对照组,两者比较有显著性差异(t=7.288,P<0.001);FIB显著高于对照组,两者比较有统计学差异(t=10.949,P<0.001)。结论:由于围产期孕妇血液呈高凝状态,产前进行凝血四项的检验分析,对DIC的预防和及时治疗有重要的临床意义。

Objective:To observe the blood coagulation four indexes in perinatal period change in pregnant women and their clinical significance.Methods:Collected from July 2010 to December 2011 in jiangsu taizhou people’s hospital line prenatal diagnosis of 100 cases of perinatal pregnant women and 100 cases of healthy non pregnant women, the sysmex fully automatic blood clots instrument uneffective among coagulant function index prothrombin time(PT), part of the blood coagulation live enzyme time(APTT), thrombin time (TT), fibrinogen (FIB) detection. Statistical analysis, analysis the index have differences between. Results:Compared with the control, perinatal pregnant woman group PT significantly reduced, which shows a statistical difference (t=10.806,P<0.001); APTT also significantly lower than those of the control group, which shows a distinctive difference (t=7.288,P<0.001); FIB significantly higher than those in the control group, both more statistics difference(t=10.949,P<0.001). Conclusion:Because of perinatal pregnant women are high blood coagulation state, prenatal on blood coagulation four test analysis, to prevent the occurrence of DIC and timely treatment has important clinical significance.