摘要
胃癌的发生发展是一个复杂的多基因作用过程 ,近年来人们已经认识到涉及胃癌发生、发展的基因包括原癌基因 (如c myc、EGFR)、抑癌基因 (如P16 )和凋亡基因 (如bcl 2 )。以上 3类基因参与胃癌发生不同时期的分子病理过程 ,且呈现出一定规律性。通过对某些胃癌发生的相关基因进行检测 ,对于肿瘤早期诊断。
Pathogenesis and development of gastric carcinoma is a complicated process of polygene action. In recent years, it was recognized that the genes with relation to pathogenesis and development of gastric carcinoma include proto oncogenes, suppress genes and apoptosis gene. The three sorts of genes correlate with molecular pathology process of gastric carcinoma in various periods, and it certainly appears rules. The detection of some gastric carcinoma related genes are important in early diagnosis and prognosis of the tumor.
出处
《中国癌症杂志》
CAS
CSCD
2000年第6期566-568,共3页
China Oncology
关键词
胃癌
癌基因
细胞凋亡
gastric cacinoma
carcinoma gene
apoptosis
