静脉丙种球蛋白治疗婴幼儿秋季腹泻临床研究

Intravenous immunoglobulin treatment of infantile autumn diarrhea in clinical research

目的研究探讨静脉注射丙种球蛋白治疗婴幼儿秋季腹泻的作用机理,观察期临床疗效并分析。方法将我院于2010年7月—2012年3月接收并治疗的秋季腹泻婴幼儿患者78例进行完全随机分组,对照组39例,实验组39例,用药后分别观察两组患者的止泻时间和疗程变化及症状缓解度。结果与对照组患者相比,实验组患者的愈后较好,用药时间较短且有效率高达94.9%,而对照组患者的总有效率为82.1%。结论静脉小剂量注射丙种球蛋白治疗婴幼儿秋季腹泻效果明显,用药安全可靠值得在临床治疗中进一步推广应用。

Objective To study investigated intravenous gamma globulin treatment of infantile autumn diarrhea mechanism of action, clinical efficacy observation period and analyzed. Methods Our hospital in July 2010 - March 2012 Diarrhea received and treated 78 patients for infants completely randomized control group 39 cases, the experimental group, 39 cases were observed after treatment for two groups of patients time and duration of diarrhea symptoms and degree of change. ResuLts Compared with the control group of patients in the experimental group of patients with better prognosis, treatment time is shorter and efficient up to 94.9%, while the control group of patients, the total effective rate was 82.1%. Condusion Intravenous injection of small doses of gamma globulin treatment of infantile autumn diarrhea effect is obvious, medication safety and reliability in the clinical treatment worthy of further application.