美托洛尔治疗对肝炎后肝硬化门静脉压力的影响

The Effect of Metoprolol Treatment on Post-hepatitis Cirrhosis Portal Vein Pressure

目的探讨分析美托洛尔治疗对肝炎后肝硬化门静脉压力的临床效果与预后影响。方法选取该院自2011年9月—2012年9月收治的肝硬化门静脉高压患者128例,其中男77例,女38例,年龄均在32-57岁,实验组64例均为进行美托洛尔治疗的患者,对照组64例为普萘洛尔治疗的患者。结果两组患者的门静脉高压均有所缓解,但实验组的缓解率明显高于对比组,PV、SV、SMV的各项指标均达到正常范围内。结论美托洛尔治疗肝炎后肝硬化门静脉高压症有一定的作用效果,值得继续深入的研究。

Objective To investigate the clinical effect of metoprolol tartrate tablets on post-hepatitis cirrhosis and portal vein pressure and the prognosis of the disease. Methods 128 patients with cirrhosis and portal hypertension aged 32 to 57, including 77 males and 38 females admitted in our hospital from September, 2011 to September, 2012 were selected. 64 patients in the experimental group were treated with metoprolol tartrate tablets, and 64 patients in the control group were treated with propranolol. Results The two groups of patients with portal hypertension have eased, but the response rate of the experimental group is significantly higher than that of the control group, the indicators of PV, SV and SMV, have reached the normal range. Conclusion Metoprolol tartrate tablets have certain effect in the treatment of post-hepatitis cirrhosis and portal hypertension and which is worthy of further study.