国产支架在急性心肌梗死病人经皮冠状动脉介入治疗中安全性及疗效观察

Observation on the Safety and Efficiency of China-made Stent in Percutaneous Coronary Intervention Treatment of Patients with Acute Myocardial Infarction

目的探讨国产支架在急性心肌梗死患者中应用的安全性和有效性。方法选择98例急性心肌梗死患者入选,年龄(52±10.3)岁的98例患者均顺利完成急诊PCI及支架置入。其中合并糖尿病21例,高血压45例,吸烟33例。术后联合应用抗血小板药物氯吡格雷和阿司匹林18个月,随访6个月,观察主要心血管事件发生率。结果 98例患者置入国产支架142枚,术中未出现并发症,血流均达到TIMI3级。术后随访6个月,主要心血管事件发生率为5.1%,再狭窄率3.1%。结论国产支架用于急性心肌梗死是安全有效的。

Objective To investigate the safety and efficiency of China-made stent in patients with acute myocardial infarction（AMI）. Methods 98 patients with AMI were enrolled in our study, with mean age 52±10.3 years old. Of them, there were 21 patients complicated by diabetes, 45 patients complicated with hypertension, and 33 patients with smoking. Emergent PCI was implemented in all the patients and China-made stent was implanted in them successfully. After PCI, the patients were administrated with antiplatelet drugs clopidogrel and aspirin for 18 months and were observed the incidence of major cardiovascular events for 6 months. Results 142 China-made stents were implanted in the 98 patients, there were no complications during the procedure, and all have acquired TIMI 3 flow. During the 6 months＇ follow-up after the operation, the incidence of major cardiovascular events was 5.1%, and the rate of restenosis was 3.1%. Conclusion It is safe and efficient with the China-made stent implanted in patients with acute myocardial infarction.