地高辛环糊精包合物制剂及其稳定性

Study on the preparation and stability of inclusion complex solution of digoxin with (β - cyclodextrin

目的:研究地高辛环糊精包合物制剂的制备及其稳定性,方法;采用经典恒温法对地高辛制剂进行稳定性实验;含量测定用HPLC.结果:4℃时DIGt_(0. 9)=2. 73.结论:包合物在制剂中稳定.

ve: TO Study the preparation and stability of inclusion complex solution of digoxin with (β - cy-clodextrin. Method: The stablility test was conducted by classical constant - temperature method. The content was determined by HPLC. Results: The solution should be stored at 4℃ with a period of validity of 2. 73 years. Conclusion: Inclusion complex was stable in solution.