盐酸克伦特罗的检测方法研究进展

Research Advance on Detection Method of Clenbuterol Hydrochloride

近年来,食品安全问题受到越来越多的社会关注。盐酸克伦特罗(CL)最初作为临床上支气管扩张剂用于治疗哮喘、支气管炎等。CL属于β-肾上腺素类兴奋剂,在动物饲料中加入CL可以明显提高动物的瘦肉率,因此不少商家大量使用它来提高肉畜的品质。然而,残留在动物体内的CL会使食用的人出现不同程度的中毒情况,严重时可导致食用者死亡。目前国内外检测CL残留含量的常用方法有气相色谱-质谱联用法(GC-MS)、高效液相色谱法(HPLC)、气相色谱法(GS)、酶联免疫吸附测定法(ELISA)、毛细管电泳法(CE)、胶体金免疫测定法(CGIA)等。综述了近年来国内外几种检测CL残留含量的方法。

With the cominuous improvemem of society,people pay more and more attention to food safety problems.Clenbuterol is used to treat bronchial asthma and chronic bronchitis as bronchial-dilating agents in clinical treatmem.After feeding the animals a certain dose of clenbuterol,the percentage of animal lean will be significantly increased.Therefore,a lot of breeders add CL to animal feed to improve the quality of the meat.Drug in animal causes eater different poisoning condition,which will result in death.At present,there are many kinds of detection methods such as GC-MS,HPLC,GS,ELISA,CE,CGIA.Several methods for detecting CL residues at home and abroad in recent years were summarized.