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经蝶入路显微手术切除鞍膈下颅咽管瘤 被引量:5

Clinical effectiveness of microsurgery through transsphenoidal approach for infradiaphragmatic craniopharyngiomas
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摘要 目的探讨鞍膈下颅咽管瘤经蝶入路显微手术治疗的效果。方法2003年1月至2013年3月显微手术治疗290例颅咽管瘤,其中29例为鞍膈下颅咽管瘤,行经蝶入路显微手术治疗。术后随访3~116月,采用MRI评估肿瘤切除程度和复发。结果肿瘤全切24例,全切率82.8%;次全切除5例。无手术死亡患者。术后6例出现脑脊液鼻漏,2例行手术修补,4例行腰穿置管,均治愈。术后6例患者出现一过性尿崩,2例出现电解质紊乱,3月后恢复正常。14例术前视力下降患者,12例术后得到不同程度改善。8例术前高泌乳素水平患者术后恢复正常,5例新出现垂体功能障碍,3月后复查恢复正常。1例复发再次经蝶入路显微手术切除肿瘤。结论鞍膈下颅咽管瘤经蝶入路手术可安全切除,创伤小,疗效好。 ObjectiveTo explore the clinical effectiveness of microsurgery through transsphenoidal approach for infradiaphragmatic craniopharyngiomas.MethodsThe clinical data of 29 patients with infradiaphragmatic craniopharyngioma who underwent microsurgery through transsphenoidal approach between 2000 and 2013 were analyzed retrospectively.ResultsTotal resection was achieved in 24 patients(82.7%) and subtotal in 5(17.3%). Of 14 patients with visual impairment, 12 improved and 2 did not change after operation. Eight patients with hyperprolactinemia recovered 3 months after operation. Cerebrospinal rhinorrhea occurred in 6 patients after operation, of whom, 4 received repair through transnasal sphenoidal approach and 2 received lumbar puncture catheter drainage. Diabetes insipidus occurred in 6 patients after operation and all recovered 3 months after conservative treatment. All patients were followed up for 3~116 months; 1 recurred and received re-operation.ConclusionsThe microsurgery through transsphenoidal approach is a feasible and effective treatment method for infradiaphragmatic craniopharyngiomas.
出处 《中国临床神经外科杂志》 2013年第11期657-660,共4页 Chinese Journal of Clinical Neurosurgery
基金 卫生部临床重点专科建设项目资助
关键词 鞍膈下颅咽管瘤 经蝶入路 显微手术 Infradiaphragmatic craniopharyngioma Microsurgery Transsphenoidal approach
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  • 1舒凯,郭东生,游超,韩林,雷霆,李龄.颅咽管瘤的显微外科治疗[J].华中医学杂志,2008,32(2):93-95. 被引量:2
  • 2雷霆,舒凯,韩林,郭东生,徐钰,张华楸,董芳永,李龄.经蝶窦入路显微手术切除颅咽管瘤[J].中华神经外科杂志,2008,24(7):493-495. 被引量:13
  • 3Buchfelder M, Schlaffer SM, Lin F, et al. Surgery for cranio- pharyngioma [J]. Pituitary, 2012, 16(1): 18-25.
  • 4Honegger J, Tatagiba M. Craniopharyngioma surgery [J]. Pituitary, 2008, 11(4): 361-573.
  • 5Laws ER, Jr. Transsphenoidal microsurgery in the manage- ment of craniopharyngioma [J]. J Neurosurg, 1980, 52(5): 661-666.
  • 6Landolt AM, Zachmann M. Results of transsphenoidal extir- pation of craniopharyngiomas and Rathke's cysts[J]. Neuro- surgery, 1991, 28(3): 410-415.
  • 7Honegger J, Buchfelder M, Fahlbusch R. Surgical treatment of craniopharyngiomas: endocrinological results [J]. J Neu- rosurg, 1999, 90(2): 251-257.
  • 8Maira G, Anile C, Albanese A, et al. The role of transsphe- noidal surgery in the treatment of craniopharyngiomas [J]. J Neurosurg, 2004, 100(3): 445-451.
  • 9Fahlbusch R, Honegger J, Paulus W, et al. Surgical treatment of craniopharyngiomas: experience with 168 patients [J]. J Neurosurg, 1999, 90(2): 237-250.
  • 10冯娟娟,华莎,杨媛,张希,肖建英,彭娜.颅咽管瘤术后护理体会[J].中国临床神经外科杂志,2012,17(12):762-763. 被引量:1

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