期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

缺血性急性肾损伤病理生理研究进展 被引量：8

下载PDF
导出
摘要 急性肾损伤（acute kidney injury,AKI）为临床常见重症,尽管治疗措施有了明显改善,其发病率与死亡率仍然很高[1,2]。缺血性肾损伤为AKI常见病因,可引起组织多种病理生理改变。深入研究AKI病理生理对启动更具针对性的治疗具有重要意义。本文对近年来缺血性AKI病理生理研究进展进行综述。
作者 王来亮 罗群
机构地区 浙江省宁波市第二医院肾内科
出处 《中国中西医结合肾病杂志》 2013年第10期924-926,共3页 Chinese Journal of Integrated Traditional and Western Nephrology
基金 浙江省医药卫生科研基金资助项目(No.2013KYB236)
关键词 病理生理改变 缺血性肾损伤 急性肾损伤 常见病因 死亡率 发病率 治疗
分类号 R692 [医药卫生—泌尿科学]
  • 相关文献

参考文献42

  • 1Singbartl K,Kellum JA.AKI in the ICU:definition,epidemiology,risk stratification,and outcomes.Kidney Int,2012,81(9):819-825.
  • 2Bellomo R,Kellum JA,Ronco C.Acute kidney injury.Lancet,2012,380(9843):756-766.
  • 3Basile DP.The endothelial cell in ischemic acute kidney injury:implications for acute and chronic function.Kidney Int,2007,72(2):151-156.
  • 4Chen J,John R,Richardson JA,et al.Toll-like receptor 4 regulates early endothelial activation during ischemic acute kidney injury.Kidney Int,2011,79(3):288-299.
  • 5Chen J,Matzuk MM,Zhou XJ,et al.Endothelial pentraxin 3 contributes to murine ischemic acute kidney injury.Kidney Int,2012,82(11):1195-1207.
  • 6Rabelink TJ,de Boer HC,van Zonneveld AJ.Endothelial activation and circulating markers of endothelial activation in kidney disease.Nat Rev Nephrol,2010,6(7):404-414.
  • 7Basile DP,Friedrich JL,Spahic J,et al.Impaired endothelial proliferation and mesenchymal transition contribute to vascular rarefaction following acute kidney injury.Am J Physiol Renal Physiol,2011,300(3):721-733.
  • 8Basile DP,Leonard EC,Beal AG,et al.Persistent oxidative stress following renal ischemia-reperfusion injury increases ANG II hemodynamic and fibrotic activity.Am J Physiol Renal Physiol,2012,302(11):1494-1502.
  • 9Awad AS,Rouse M,Huang L,et al.Compartmentalization of neutrophils in the kidney and lung following acute ischemic kidney injury.Kidney Int,2009,75(7):689-698.
  • 10Li L,Huang L,Vergis AL,et al.IL-17 produced by neutrophils regulates IFN-gamma-mediated neutrophil migration in mouse kidney ischemia-reperfusion injury.J Clin Invest,2010,120(1):331-342.

二级参考文献30

  • 1朱乃金,胡宗华,周湘,胡宗元.两种肾损伤诊断试剂的合成及肾损伤的动态监测[J].吉林医学,2004,25(6):9-11. 被引量：5
  • 2Lassnigg A,Schmidlin D,Mouhieddine M,et al.Minimal changes of serum creatinine predict prognosis in patients after cardiothoracic surgery:a prospective cohort study.J Am Soc Nephrol,2004,15:1597-1605.
  • 3McCullough PA.Radiocontrast-induced acute kidney injury.Nephron Physiol,2008,109:61-72.
  • 4Han WK,Bailly V,Abichandani R,et al.Kidney injury molecule-1 (KIM-1):a novel biomarker for human renal proximal tubule injury.Kidney Int,2002,62:237-244.
  • 5Ronco C, Levin A, Warnock DG, et al. Improving outcomes from acute kidney injury (AKI) :report on an initiative. Int J Artif Or- gans,2007,30 (5) :373 - 376.
  • 6Lameire N, Van Biesen W, Vanholder R. Acute renal failure. Lancet, 2005,365 (9457) : 417 - 430.
  • 7Uzun H, Ozmen Keles M, Ataman R, et al. Serum cystatin C level as a potentially good marker for impaired kidney function. Clin Biochem,2005,38 (9) :792 - 798.
  • 8Herget - Rosenthal S, Marggraf G, Htising J, et al. Early detection of acute renal failure by serum cystatin C. Kidney Int ,2004,66 (3) :1115 -1122.
  • 9Knight EL, Verhave JC, Spiegelman D, et al. Factor influencing serum cystatin C levels other than renal function and the impact on renal function measurement. Kidney Int, 2004,65 (4) : 1416 - 1421.
  • 10Vaidya VS, Ferguson MA, Bonventre JV. Biomarkers of acute kid- ney injury. Annu Rev Pharmacol Toxieol,2008 ,48 :463 - 493.

共引文献28

同被引文献117

  • 1彭勇,刘作金,龚建平,刘海忠,甘霖,李寿柏.Kupffer细胞CD14及Toll样受体4介导大鼠肝移植缺血再灌注损伤的机制[J].中华外科杂志,2005,43(5):274-276. 被引量：15
  • 2方艺,丁小强,钟一红,邹建洲,汤颖,林静,林攀,俞小芳.住院患者急性肾损伤的发病情况调查[J].中华肾脏病杂志,2007,23(7):417-421. 被引量：53
  • 3刘煜敏,张悦,何立群,陆海英,刘克剑,李靖,林敏.抗纤灵抗大鼠肾间质纤维化的实验研究[J].中国中西医结合杂志,2007,27(10):901-904. 被引量：15
  • 4Bucaloiu ID, Kirchner HL, Norfolk ER, et al. Increased risk of death and de novo chronic kidney disease following reversible a- cute kidney injury. Kidney Int, 2012,81 (5) :477 -485.
  • 5Lattanzio MR, Kopyt NP. Acute kidney injury: new concepts in definition, diagnosis, pathophysiology, and treatment. J Am Osteo- path Assoc ,2009,109 ( 1 ) : 13 - 19.
  • 6Dirkes S. Sepsis and inflammation:impact on acute kidney inju- ry. Nephrol Nurs J,2013,40(2) :125 -132.
  • 7Takada M, Nadeau KC, Shaw GD, et al. The cytokine - adhesion molecule cascade in ischemia/reperfusion injury of the rat kid-ney. Inhibition by a soluble P - selectin ligand. J Clin Invest, 1997,99 ( 11 ) :2682 - 2690.
  • 8Liu M, Chien CC, Burne - Taney M, et al. A pathophysiologic role for T lymphocytes in murine acute cisplatin nephrotoxicity. J Am Soc Nephrol,2006,17 ( 3 ) :765 - 774.
  • 9Li L,Huang L,Sung SS,et al. NKT cell activation mediates neu- trophil IFN - gamma production and renal ischemia - reperfusion injury. J Immuno1,2007,178 (9) :5899 - 5911.
  • 10Huang Y, Rabb H, Womer KL. Ischemia - reperfusion and im- mediate T cell responses. Cell Immunol,2007,248 (1) :4 -11.

引证文献8

二级引证文献46

中国中西医结合肾病杂志
2013年 第10期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部