颅内囊性肿瘤伽玛刀治疗的容积效应探讨

The research of volume effect after the gamma knife radiosurgery for intracranial cystic tumor

目的探讨颅内囊性肿瘤伽马刀治疗的容积效应,为临床提高此类患者治疗效果及预后提供可靠依据,保障患者治疗安全性及生命安全。方法根据颅内囊性肿瘤患者实际情况确定囊液抽吸方式(直接穿刺抽吸或置入Ommaya储液囊),待囊液抽出后实施伽马刀治疗,应用Logistic综合方程分别计算颅内囊性肿瘤患者抽囊前后风险概率,并对所得结果进行对比,得出结论。结果颅内囊性肿瘤患者抽液后肿瘤体积明显缩小,且风险概率显著降低,提示颅内囊性肿瘤内容物容积与风险呈正比,即内容物容积越大,则风险越高,对比结果具有统计学意义(P<0.05)。结论临床医师对颅内囊性肿瘤患者进行伽马刀治疗时,应于治疗前首先对其颅内肿瘤囊液抽取,从而有效降低其治疗风险,保障治疗安全性,利于患者达到理想疗效,提高其生活质量及生命安全,值得临床推广应用。

Objective To investigate the gamma knife treatment of intracranial cystic tumor volume effect , improving clinical treatment and prognosis of such patients provide a reliable basis to ensure patient safety and the safety of the treatment. Methods According to the actual situation of patients with intracranial cystic tumor cyst fluid aspiration to determine ways （ direct aspiration or placement Ommaya reservoir fluid sac ）,to be implemented after the cyst fluid extraction gamma knife treatment,the application of Integrated Logistic equations were calculated intracranial cystic sac tumor patients before and after pumping risk probability,and the results were compared,draw conclusions. Results Patients with intracranial cystic tumors after pumping fluid tumor volume was significantly reduced,and the risk probability was significantly decreased,suggesting that the contents of intracranial cystic tumor volume is proportional to the risk that the contents of the volume was larger,the higher the risk,comparing the results statistically significant （P〈0.05）. Conclusion Clinicians patients with intracranial cystic tumors gamma knife treatment should be the treatment of intracranial tumors before the first of its cyst fluid extraction,thus effectively reducing the risks of treatment,treatment safety protection,which will help the patient to achieve the desired effect, improve their quality of life and life safety,worthy of clinical application .