万托林联合普米克雾化吸入治疗小儿哮喘急性发作的疗效观察

Clinical Curative Effect of Ventolin Combined with Pulmicort in Treatment of Acute Attack of Asthma in Children

目的观察万托林联合普米克治疗小儿哮喘急性发作的临床疗效。方法将74例哮喘急性发作患儿随机分为研究组与对照组,每组37例。对照组采用常规药物进行治疗,研究组在对照组基础上加用万托林联合普米克进行雾化吸入治疗,治疗结束后评定疗效。结果研究组的临床总有效率为91.89%,显著优于对照组的78.38%,两组临床疗效差异均显著,具有统计学意义(P<0.05);两组患儿FVC、FEV1、PEFR等肺功能指标值均较治疗前升高,其中观察组的变化程度尤为显著,与治疗前及同期对照组比较,差异均具有统计学意义(P<0.05)。结论万托林联合普米克雾化吸入治疗小儿哮喘急性发作的临床疗效显著,值得在临床推广使用。

Objective To observe the clinical curative effect of Ventolin combined with Pulmicort in treatment of acute attack of asthma in children. Methods 74 patients with asthma were randomLy divided into study group and control group, each group of 37 cases. The control group received conventional drug treatment, on the basis of this, the study group was treated with Ventolin combined with Pulmicort inhalation, and the curative effects were evaluated. Results The clinical total effective rate in study group was 91.89%, significantly better than that（78.38%） in the control group, with statistical significance（P〈0.05）. The lung function index such as FVC, FEV1, PEFR value in two groups all increased at the end of treatment, the observation group change degree was particularly significant, compared with the control group and before treatment, the differences were statistically significant（P〈0.05）. Conclusion Combined Ventolin and Pulmicort inhalation has significant clinical efficacy in treating acute attack of asthma in children, it is worth in clinical use.