加强代谢综合征与慢性肝病关系的研究

Strengthening research on relationship between metabolic syndrome and chronic liver disease

当前代谢综合征正呈全球化的流行趋势,并已成为我国慢性肝病愈来愈重要的病因或诱因。最近大量研究表明,代谢综合征不但是非酒精性脂肪性肝病发生发展的重要危险因素,还与酒精性肝病、慢性乙型肝炎、慢性丙型肝炎以及隐源性肝病患者肝硬化和肝癌的高发密切相关。此外,合并代谢综合征的慢性肝病患者发生2型糖尿病和动脉粥样硬化性心血管疾病的危险性显著增加。提示肝病医生需加强代谢综合征与肝病的关系及其诊疗对策的临床研究。

Metabolic syndrome is becoming a global epidemic disease, and it has been an important cause or risk factor tor chronic liver dis- ease in China. Recently, many studies have shown that metabolic syndrome is not only the important cause or risk factor for non - alcoholic fatty liver disease, but also closely associated with increased incidence of cirrhosis and liver cancer in patients with alcoholic liver disease, chronic hepatitis B and C, and cryptogenic liver disease. Moreover, chronic liver disease patients with metabolic syndrome have a signifi- cantly increased risk of type 2 diabetes and arteriosclerotic cardiovascular disease. These resuhs suggest that hepatologists should pay more attention to the clinical research on the relationship between metabolic syndrome and liver disease and its management.