益气通腑汤联合西药治疗ARDS伴细菌性肺炎的临床疗效及预后观察

The Clinical Effect and Prognosis of YiQi TongFu Tang Combined with Western Medicine in the Treatment of ARDS with Bacterial Pneumonia

目的:探讨中西医结合疗法对急性呼吸窘迫综合征(ARDS)伴细菌性肺炎临床疗效和预后的影响。方法:将收治的66例ARDS伴肺炎患者随机分为观察组和对照组,对照组给予机械通气和常规抗生素、营养支持等对症治疗,观察组在此基础上给予自拟益气通腑汤,观察两组患者的临床疗效和预后改善情况。结果:观察组血浆肿瘤坏死因子-α(TNF-α)血清含量为(145.9±7.4)ng/L,白介素-6(IL-6)血清含量为(7.24±1.19)ng/L,对照组TNF-α血清含量为(182.6±8.9)ng/L,IL-6血清含量为(16.23±2.21)ng/L,两组差异有统计学意义(P<0.05);观察组动脉血气指标、气道压力指标及临床诊疗情况也显著优于对照组,两组差异有统计学意义(P<0.05)。结论:益气通腑汤联合西药能显著缓解临床症状,提高临床疗效和改善预后,具有重要的临床应用价值。

Objective ： To explore the clinical effect and prognosis of YiQi TongFu Tang in the treatment of ARDS with bacterial pneumonia. Methods ： 66 cases of ARDS associated with pneumonia patients were randomly divided into the ob- servation group and the control group in our hospital, the control group was given conventional symptomatic treatment, the observation group was given YiQi TongFu Tang in the basis of the control group, to observe the clinical efficacy and prog- nosis. Results ： The TNF - α content of the observation group was 145.9 ±7.4ng/L, the IL - 6 content was 7.24 - 1.19 ng/L, the TNF -α content of the control group was 182.6 -8.9ng/L, the IL -6 content was 16.23±2.21ng/L, the difference between the two groups was significantly（ P 〈 0.05 ） ; the improvement of airway pressure and arterial blood gas in observation group was better than the control groups（ t = 6. 754, P = 0. 024）. Conclusion： YiQi TongFu Tang combined with western medicine can significantly improve the clinical efficacy and the prognosis.