药物扩张宫颈法应用于绝经期妇女取环术的研究

Application study of drug expansion cervix uteri in taking intrauterine devices from menopausal women

目的讨论应用米非司酮进行药物扩张宫颈口对绝经期妇女行宫内节育环(IUD)取出术的应用价值和疗效。方法回顾性分析98例绝经期有取环要求的妇女为研究对象,随机分为实验组和对照组各49例,实验组采用术前服用米非司酮药物扩张宫颈口联合取环术,对照组采用单纯取环术,对比分析两组患者术前宫颈适宜度和手术情况,评估患者的临床治疗有效率。结果实验组患者手术时间平均为(5.56±1.20)min,显著低于对照组的(12.57±1.52)min;实验组出血量较少、宫颈软化度及取环成功率均显著高于对照组;实验组和对照组患者的总有效率分别为85.71%、55.10%,差异有统计学意义(P<0.05)。结论术前采用米非司酮进行药物扩张宫颈法可促进宫颈软化度,减少IUD取出过程中的嵌顿机会,减少宫颈裂伤,大大提高取环术的临床有效率,值得临床推广应用。

Objective To discuss the application value and effect of mifepristone as a drug for expanding cervix uteri in taking intrauterine devices （IUD） from menopausal women.Methods 98 menopausal women in their requirements of taking out of IUD were retrospectively analyzed and evenly divided into experimental group and control group in ran- dora.In the experimental group,the mifepristone was used for expanding cervix uteri before surgery,and then extraction of IUD was adopted,while in the control group,only extraction of IUD was applied.The suitability of cervix uteri before surgery and surgical situation in both groups were comparatively analyzed and the therapeutic effective rate in clinic from the two groups were evaluated.Results The mean operation time in experimental group was （5.56＋1.20） min,much lower than （12.57±1.52） min of the control group.The blood loss,softening of cervix uteri,and success rate of extraction of IUD in the experimental group was obviously higher than that in the control group.The total effective rate in the ex- perimental and control group was 85.71% and 55.10% respectively,with statistical difference （P〈0.05）.Conclusion Pre- operative application of mifepristone as a drug for expanding cervix uteri can promote the softening of cervix uteri,de- crease the chances of incarceration in the process of taking out of IUD,reduce cervical laceration,and greatly improve the clinical effective rate of extraction of IUD,which is worthy of expansion in clinic.